Program

PRE-SYMPOSIUM ACTIVITIES — Jornada previa
09:00-11:00	Swine Health Forum (in Spanish)
11:00	REGISTRATION
16:00	Welcome and opening remarks
16:15-17:45	Keynote lectures The porcine reproductive and respiratory syndrome virus (PRRSV) saga: using macrophages as targets is ingenious but challenging for a virus with an evolutionary plan Prof. Hans Nauwynck- Ghent University Veterinary and public health challenges of swine influenza viruses Prof. Lars E. Larsen – University of Copenhagen
17:45 WELCOME RECEPTION

–	REGISTRATION
8:30-9:30	Invited lectures The evolutionary dynamics behind epidemic waves of PRRSV Prof. Kimberly VanderWaal, University of Minnesota PRRS epidemiology in practice Prof. Giovanni Trevisan, Iowa State University
9:30-10:30	Oral communications Whole-genome classification system for porcine reproductive and respiratory syndrome virus type 2 (Betaarterivirus americense) strains combining ORF5, nsp3-4-5 and indels Vicent Baby, Université de Montréal Known enemy or new threat? A tussle between introduction, persistence and recombination of PRRSV strains on pig farms Harsh Bardhan Gupta, Utrecht University Assessment of the mutation, selection, substitution and recombination patterns and dynamics of “classical” versus “Rosalía and Rosalía-like” Spanish PRRSV-1 strains Martí Cortey, Universitat Autònoma de Barcelona An artificial intelligence (AI) agent-based support system for porcine reproductive and respiratory syndrome (PRRS) health management in Colombia Francisco Gómez, Universidad Nacional de Colombia
10:30-11:00 Coffee Break
11:00-12:00	Invited lectures Molecular mechanisms of PRRSV persistence: challenges for elimination Prof. Ying Fang- University of Illinois at Urbana-Champaign Genome editing for disease resistance in pigs Dr. Christine Tait-Burkard – Roslin Institute, University of Edinburgh
12:00-13:00	Oral communications A new reverse-genetics system for PRRSV identifies a GP3 trafficking signal that promotes viral replication Dongwan Yoo, University of Illinois Urbana-Champaign Porcine reproductive and respiratory syndrome virus nsp1α degrades ribosomal components to inhibit cellular translation Qiongqiong Zhou, China Agricultural University CD169 blockade as an in vitro model to discriminate PRRSV-1 isolates with different virulence profiles Francisco Javier Martínez-Lobo, Universitat de Lleida Highly virulent PRRSV-1 Rosalía strain induces enhanced CTLA-4 expression and immune dysregulation in piglets during the early and late stages of infection Jaime Gómez-Laguna, Universidad de Córdoba
13:00-14:00 Lunch
14:00-15:00	Invited lectures Immunopathogenesis of the reproductive form of PRRS Prof. Andrea Ladinig, University of Veterinary Medicine Vienna Emerging vaccine platforms for swine viral diseases Prof. Xiang-Jin Meng, Virginia Tech
15:00-17:00	Oral communications Towards an improved understanding of adaptive immune dysregulation during arterivirus infection Jane Edwards, The Pirbright Institute Systems vaccinology reveals mechanistically distinct immune profiles of interferon-augmented PRRSV vaccines Laura Miller, Kansas State University Generation of PRRSV epitope–MHC class I tetramers to investigate CD8 T cells at the maternal–foetal interface in infected sows Mahsa Rafieiyan, The Pirbright Institute Mucosal induction of trained immunity reduces susceptibility to PRRSV infection in pigs Aida Tort Miró, IRTA-CReSA PRRSV-anergic status in vaccinated sows: impact on vaccine efficacy and piglet challenge outcomes Marylène Tignon, Sciensano Isolation and characterisation of naturally occurring PRRSV-neutralising monoclonal antibodies to support structural vaccinology Simon Graham, The Pirbright Institute Flash talks Evaluating the economic impact of early interventions against PRRSV using multivariate syndromic surveillance in Spanish swine breeding herds Mafalda Pedro Mil-Homens, Universitat Autònoma de Barcelona Estimation of PRRS hazard and vulnerability through a health risk index based on data analytics Fausto Moreno, Universidad Nacional de Colombia Prevalence and epidemiological role of porcine respiratory coronavirus, porcine haemagglutinating encephalomyelitis virus and influenza D virus in Spanish herds Menjun Wang, Universitat Autònoma de Barcelona Comparison of cell systems for isolation and replication assessment of porcine parainfluenza virus 1 Ge Ye, Universitat Autònoma de Barcelona A novel swine trophoblast organoid system to investigate PRRSV–placenta interactions Abigail Williams, North Carolina State University Impact of formalin fixation time on PRRSV-1 detection by RNAscope® in situ hybridisation combined with deep-learning-based digital pathology Giuditta Capaldi, Universidad de Córdoba
17:00	European PRRS Research Awards
20:00 GALA DINNER

–	REGISTRATION
8:30-9:30	Invited lectures Overview of viral swine diseases worldwide Dr. Gregorio Torres- Head of the Science Department, World Organisation for Animal Health Investigations into influenza A virus reassortment in commercial pigs Prof. Montserrat Torremorell – University of Minnesota
9:30-10:30	Oral communications Validation of genomic prediction for disease resilience traits and their genetic relationship with selection-index traits Claudia Sevillano, Topigs Norsvin Enhancing biosecurity in swine operations: investigating wildlife interactions at mortality-management structures on swine farms Rafael Medeiros de Avila Melo, University of Minnesota Road-level transmission risk of PRRS in the United States swine network: a spatiotemporal Bayesian framework linking animal movement to farm infection Nicolás Cárdenas, North Carolina State University Flash talks A structural bioinformatics framework for precision host-factor engineering towards influenza-resistant pigs Joaquín Gadea, Universidad de Murcia Monitoring PRRSV dynamics in different farm environments: evaluating diagnostic samples in farrowing and nursery units Laura Junquera, Universidade de Santiago de Compostela Interlaboratory comparison of PRRSV genome and antibody detection across diagnostic laboratories in Central Europe Kristin Heenemann, Leipzig University
10:30-11:00 Coffee Break
11:00-13:00	Round table: Experiences in the control and eradication of PRRS Moderator: Dr Tijs Tobias, Royal GD, Deventer Danish PRRS reduction strategy: background, progress and lessons learned Nicolai Rosager Weber – Danish Agriculture & Food Council PRRS control and eradication in the USA Dr. César Corzo -University of Minnesota Diverse PRRSV and its control and elimination strategies in China Prof. Hanchun Yang – China Agricultural University
13:00-14:00 Lunch
14:00-15:30	Invited lectures African swine fever and eradication in the European context Fátima Guerrero – Ministerio de Agricultura, Pesca y Alimentación Protective immunity associated with viral control in PRRS Prof. Jun Han – China Agricultural University New PEDV epidemic patterns in China: virulent G2c variants and SIN-DEL clade-2 recombinants and their implications for global PEDV evolution Prof. Yao-Wei Huang- South China Agricultural University
15:30-16:50	Flash talks A highly virulent porcine reproductive and respiratory syndrome virus strain exhibits macrophage and endothelial cell tropism in infected piglets Paula Curto, Universitat de Lleida Comparison of infection by PAM- and MARC-145-passaged PRRSV isolates in PK15CD163+ and PK15Sialoadhesin+CD163+ cell lines Wenjing Su, Ghent University Lipid nanoparticle encapsulation enhances DNA vaccine efficacy against highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b Hiep Vu, University of Nebraska–Lincoln Local viral load shapes T-cell composition and differentiation at the maternal–foetal interface during PRRSV infection Melissa Stas, University of Veterinary Medicine Vienna Impact of persistent infection with an attenuated African swine fever virus on viral population dynamics following subsequent inoculation with virulent strains Tomoya Kitamura, NIAH–NARO Oral communications Clinical, histomorphological and molecular profiling of swine enteric coronavirus infection: insights from microRNA and target-gene expression in piglets Carmen Álvarez Delgado, Universidad de Córdoba Non-canonical TRS usage and functional analysis of the ORF6 region of a type I PRRSV strongly suggest translation of a novel essential protein, 6a Eszter Göltl, HUN-REN Veterinary Medical Research Institute Evaluation of the dose-dependent virulence of PRRSV-1 “Rosalía” in weaned piglets and the modulating role of maternal antibodies Carles Vilalta, IRTA-CReSA
16:50	IPRRS 2026 Awards
17:00	Farewell message